Need help getting rid of a virus?

alright so i have a virus i ran my anti virus program which is avast but its not getting rid of it so i ran hijackthis and heres the results

C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=6...

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=5...

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=5...

R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=6...

R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant =

R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =

F3 - REG:win.ini: load=C:\WINDOWS\system32\pmkjj.exe

O3 - Toolbar: (no name) - %26#123;0BF43445-2F28-4351-9252-17FE6E806AA0%26#125; - (no file)

O4 - HKLM\..\Run: [xFXMixer] C:\PROGRA~1\xFXMixer\xfxmixer.exe /min

O4 - HKLM\..\Run: [Windows Defender] "C:\Program Files\Windows Defender\MSASCui.exe" -hide

O4 - HKLM\..\Run: [VTPreset] VTPreset.exe

O4 - HKLM\..\Run: [LXBRKsk] C:\PROGRA~1\LEXMAR~1\LXBRKsk.exe

O4 - HKLM\..\Run: [Lexmark 3100 Series] "C:\Program Files\Lexmark 3100 Series\lxbrbmgr.exe"

O4 - HKLM\..\Run: [Cmaudio] RunDll32 cmicnfg.cpl,CMICtrlWnd

O4 - HKLM\..\Run: [Assassin 4.0] C:\Program Files\Black List Software\Assassin 4.0\assassin.exe